What is unexplained infertility?

If the uterine tube film made within the scope of the evaluation of the couples who have difficulty conceiving is normal, if the woman has regular menstruation, if there is no problem in the USG examination, if the male sperm values ​​are normal, this infertility is called unexplained infertility.

Couples with infertility problems rightly ask: If everything is normal, why can’t we have a baby?

Underlying unexplained infertility may be problems at the molecular level that are currently undetected. For example, in order for the sperm to enter the egg and fertilize it, it must attach to the egg’s membrane (a molecule called the Z protein is required for this attachment). Hundreds of proteins, such as this Z protein, are involved in conception. Investigating these hundreds of proteins is unnecessary as it is very costly. In addition, many unknown problems are overcome with vaccination and in vitro fertilization method. For example, in in vitro fertilization, sperm are directly deposited into the egg by microinjection method (Z protein is not needed).

In the treatment of unexplained infertility, vaccination should be done 2-3 times. The success of vaccination in unexplained infertility is around 20% per application. If the vaccination treatment is unsuccessful, in vitro fertilization treatment should be started.

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