One of the most important problems faced by couples who want to have a baby with the IVF method; A woman’s ovarian reserve is reduced. Many methods are being developed on this subject. Gynecology, Obstetrics and IVF Specialist Op. Dr. Seval Taşdemir told you what you need to know about the PRP method in IVF treatment.
What is stem cell therapy (PRP)?
There is a promising form of treatment that is being heard frequently in many fields of medicine: Stem cell therapy (PRP). Stem cells; They are extraordinary cells that have the ability to transform into any cell in our body, thus also an egg cell, with the appropriate biological stimulus. Stem cells in the ovary can turn into mature egg cells. It is the injection of a special liquid called PRP (Platelet Rich Plasma) obtained from the person’s own blood to the ovaries that provides this transformation.
Ovarian rejuvenation with PRP treatment
This process consists of two steps. First, a certain amount of blood is drawn. This blood is divided into tubes and centrifuged, and white cells and platelets are cleared from red blood cells. The preparation process takes less than 1 hour. The second step is to give this liquid to the ovaries of the person. In the meantime, vaginal ultrasonography is used and a short-term sedation is applied.
Mechanism of action of PRP
Growth factors are substances found in platelets and white blood cells that provide the body’s natural repair. These substances work in the damaged area, preventing infection, stopping bleeding and providing vascularization and new cell growth. Thanks to the injection of this fluid containing growth factors into the ovaries, it is possible to develop eggs or to produce quality eggs in women who have not developed their own eggs before. This increases the chances of conceiving both spontaneously and with IVF. It should be kept in mind that it is an innovative medical treatment, but at the same time it may not work in every case.
Who is it suitable for?
PRP can be applied to every physically and mentally healthy woman if she falls into one of the following 4 categories:
– Those over 35 years of age, infertile, with reduced number and quality of egg reserve and low AMH levels
– Those under 35 years of age with low ovarian reserve and low AMH value
– Women with premature ovarian failure
– Those under 50 years of age, perimenopausal and menopausal
When is it applied?
It can be applied at any time in non-menstrual women. In menstruating people (regular or irregular), the most appropriate period is the egg development phase after menstruation. AMH, LH, E2 and FSH values can be monitored to see the positive effects of the treatment.