What is excessive hair growth?

ExtremeWhat is hair growth?

Hair growth usually occurs on the face, between the two breasts, around the navel, on the shoulders, on the back, and on the legs. The hair becomes darker in color and increases in thickness. He has a masculine hairiness.

hair growthWhat are the reasons for the increase?

-Increased hair growth of unknown cause

They are normal women with regular menstruation, normal blood male hormones, and no accompanying hormonal disorders. The only problem is hair growth. 4-8% of all hair growth falls into this type. The activity of 5 alpha reductase 1 enzyme in hair follicles increased. In other words, the hair follicles have become more sensitive to the male hormone.

Women also have certain limits of male hormones. In this case, all male hormones in women are at normal levels. In these women, the hair follicles are more sensitive to the male hormone than other women. Even if hormone levels are normal, the hair becomes thicker and darker (becomes terminal hair).

-Increased hair growth with extreme insulin resistance

It is known as HAIR-AN syndrome. Insulin resistance, Hyperandrogenism, acanthosis nigricans is associated with brown spots on the skin.

Adult-onset congenital adrenal gland hyperplasia

The family is transitive. It is seen in 21 alpha hydroxylase enzyme deficiency. It usually occurs in girls after they start menstruating. Irregular periods are often present. Although its frequency varies between ethnic groups, it is between 1.6%-10%.

Tumors that secrete male hormone

They are rare. They are seen in 0.2%-0.6% of women with hair growth. They can originate from the adrenal gland or the ovaries. Hair growth in a very short time, deepening of the voice, male pattern baldness, male pattern muscle gain, and enlargement of the clitoris are among the complaints.

-High levels of milk hormone

High levels of prolactin, known as the milk hormone, may be associated with increased hair growth. The milk hormone may also increase slightly in polycystic ovarian disease.

-Hypothyroidism (underactive goiter gland)

It acts by causing an increase in the milk hormone. It also directly affects the hair follicles.

-Cushing’s disease and Acromegaly

It is rare.

-Polycystic ovarian disease

Polycystic ovary disease is the most common hormonal disorder in women, affecting 5-10% of the population. Male hormones in the blood may increase in polycystic ovarian disease. This can cause hair growth.

-Use of drugs containing some male hormones

Diagnosis

In the diagnosis, the patient is examined, USG is performed, and the degree of hair growth is determined by the Ferriman-Gallwey measurement. Male hormones are detected in the blood. (Total testosterone, free testosterone, SHBG, DHEA-S). Prolactin and TSH values ​​are requested.

At the beginning of early menstruation (early follicular period), 17 hydroxyprogesterone (17-OHP) is measured in the morning. If 17-OHP is above 300 ng/ml, ACTH stimulation test is performed. 0.25 mg of cortrosynim is given. 0 and 1 hour 17-OHP values ​​are measured. Values ​​above 1000 ng/ml suggest congenital adrenal hyperplasia and genetic tests are performed.

If total testosterone is above 150 ng/dL or DHEAS 600 mcg/dL, evaluation for adrenal gland tumor should be made.

Ferriman-Gallwey measurement. 9 regions are evaluated according to the degree of hair growth. If you score 8 and above, the diagnosis of hair growth is made.

Treatment

Treatment is for the cause. Computed tomography and MRI may be requested in cases involving the adrenal gland. It is treated in the presence of polycystic ovaries.

Click here for the treatment of polycystic ovarian disease.

Although birth control pills alone reduce hair growth, they are not fully effective. Not all birth control pills are suitable for hair growth treatment. The fact that the progesterone in it is a birth control pill that reduces the male hormone affects the treatment positively. for example Diane 35 There is a low dose of Cyproterone acetate in it that reduces the male hormone. Still beleraIt contains Chlormadinone acetate, which reduces the male hormone. Yasmin and Yazz Birth control pills contain Drospirenone, which reduces the male hormone. Your doctor will recommend the most effective birth control pill to you.

Usually, birth control pills are used together with drugs that effectively reduce the male hormone.

Author

663751
prof. Dr. Ibrahim ESINLER

Gynecology and Obstetrics

This article was added on 29.09.2011. 6782times read.

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