VITILIGO

Vitiligo can occur at any age, varying in size and number, well circumscribed, milky white in color.
It is an acquired skin disease characterized by melanocyte destruction that appears in patches. disease
depigmentation (color color) in visible areas although it is asymptomatic (not causing any complaints)
absence) causes serious cosmetic impairment and is a psychological problem, especially in people with dark skin color.
may be the source of the disorder.

Although little is known about the pathogenesis (cause of occurrence) and genetics of vitiligo, it is striking
It is a disease known for thousands of years because of its appearance. Age, gender and racial discrimination in societies
Although it is thought to occur at a rate of 0.14-8.8% without
between. Vitiligo can develop at any age. onset of disease between birth and 81 years of age
It can happen at any age. Congenital (congenital) vitiligo is very rare. 50% of patients are 10-30 years old
between.
According to one theory, genetic factors, stress, accumulation of toxic compounds, infections, autoimmunity, altered
cell environment, impaired melanocyte migration and proliferation all lead to vitiligo disease
has been suggested to open.

Patients with vitiligo often begin their illness with a specific life event, crisis, or illness.
they can connect. Most illnesses are caused by a job loss, death of a close family member, accident, or serious illness.
can relate.

Clinically round to oval in shape, with slightly brushy or widely spaced scalloped margins.
in appearance, varying in diameter from a few mm to cm, and usually other epidermal (uppermost part of the skin)
Lesions without changes are observed. The color is usually uniformly milky white or chalky.
is white. In very fair-skinned people, the lesions are not very pronounced, but in dark-skinned people with skin with vitiligo.
The contrast between lesional skin is striking. Hair on areas with vitiligo usually
turns white. Lesions are most common on the face, back of the hand, nipples, axilla (armpit), navel, sacrum (tail).
thorax), inguinal (groin) and anogenital region.
affect areas with bony prominences, such as the backs, feet, knees, elbows, and ankles
it could be.

Clinically vitiligo types
Localized (focal, segmental)
Generalized (acrofacial (face and hands) and diffuse)
Universal
Mixed

Diagnosis is usually made by anamnesis (patient’s history), clinical findings and various laboratory examinations.
Wood light (purple light) and increased contrast between normal skin and lesioned skin are also helpful in diagnosis.
is used.

Vitiligo is a social problem because it causes cosmetic disorders and emotional stress in people.
It has been tried to be treated with different methods until today. In vitiligo exactly
An ideal, etiology-focused, effective drug is not available so far. Patient’s age and type of vitiligo treatment
The first two factors will influence the choice. The success that can be achieved in vitiligo treatment depends on the type of the disease,
It may vary depending on the prevalence, skin color, age, the treatment to be chosen and the duration of treatment.

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