Optical coherence tomography angiography phase scaling application findings in patients with non-proliferative diabetic retinopathy.

SUMMARY Purpose: Using optical coherence tomography angiography (OCTA) in patients with non-proliferative diabetic retinopathy (NPDRP), the foveal avascular zone (FAZ) area, FAZ circumference, circularity index of FAZ (DI), foveal density (FD) and macular capillary plexuses can be determined. Comparison of vascular densities with age- and sex-matched normal individuals. Material and Methods: Patients followed up in our retina clinic with mild to moderate NPDRP were examined. Inclusion criteria were determined as having a best corrected visual acuity of at least 20/20. Individuals were imaged with OKTA’s FAZ, Non-Flow and Density scaling application. Patients with poor image quality and segmentation errors due to cystoid macular changes and patients with impaired retinal anatomical features were excluded from the study. FAZ parameters and vascular density values ​​of superficial (YKP) and deep capillary plexuses (DKP) were measured. Results: Fifty eyes of 50 subjects, 24 cases in the NPDRP group and 26 cases in the control group, were included in the study. FAZ area in the superficial capillary plexus, whole retinal FAZ area, FAZ perimeter and DI NPDRP group were significantly higher than the control group (p<0.05 for all). In addition, FD in the FAZ scaling application was found to be significantly lower in the NPDRP group than in the control group (p=0.000). Conclusion: OCTA provides quantitative data on PHASE area, FAZ circumference, circularity index of FAZ, foveal density, and vascular densities of macular capillary plexuses. Foveal density should be evaluated with FAZ scaling application, not density scaling application of OCTA in patients with NPDRP.

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