He first used the ketogenic diet to treat epilepsy in 1921.
If you say what is the content; It consists of approximately 55% to 60% fat, 30% to 35% protein, and 5 to 10% carbohydrates. Specifically, on a diet of 2000 kcal per day, the amount of carbohydrates is up to 20 to 50 g per day.
Basically, carbohydrates are the primary source of energy production in body tissues. When the body is deprived of carbohydrates, insulin release is significantly reduced and the body enters a catabolic state. Glycogen stores are depleted and force the body to go through certain metabolic changes, one of which is ketogenesis. Ketone bodies formed as a result of ketogenesis replace glucose as the primary energy source. During ketogenesis, due to low blood sugar feedback, the stimulation for insulin secretion is also low, which sharply reduces the stimulation for fat and glucose storage.
Ketone bodies produce more ATP compared to Glucose. This allows the body to maintain efficient fuel production even during a calorie deficit.
In addition to reducing weight, especially trunk obesity and insulin resistance, low-carb diets can also help improve blood pressure, blood sugar regulation, triglycerides and HDL cholesterol levels, but in the long run, LDL cholesterol may increase on this diet.
Symptoms include nausea, vomiting, headache, fatigue, dizziness, insomnia, difficulty with exercise tolerance, and constipation, sometimes referred to as the keto flu. These symptoms resolve within a few days to a few weeks. Ensuring adequate fluid and electrolyte intake can help relieve some of these symptoms.
Long-term side effects include hepatic steatosis, hypoproteinemia, kidney stones, and vitamin and mineral deficiencies. People who also have Diabetes and are taking insulin or oral hypoglycemic agents will experience severe hypoglycemia if medications are not adjusted properly before starting this diet.
You should not follow such diets for a long time unless your doctor or dietitian recommends it.