In vitro fertilization is a form of treatment applied to women who cannot become pregnant with classical methods. It is based on the principle of transferring embryos to the uterus, which are formed as a result of combining male (sperm) and female (egg) progeny cells under laboratory conditions.

Fertilization performed under laboratory conditions can be achieved spontaneously (in vitro fertilization, IVF) after these cells are left in the same environment, or by injecting a single sperm into a single egg (microinjection, ICSI).

Microinjection (ICSI)

Microinjection technique is used in cases of male infertility where sperm cells cannot exceed the egg membrane for any reason. It is one of the most suitable methods for men with low sperm count and motility or who have deformities in their sperm to have children.

A single sperm cell is injected into the egg obtained from the woman under the microscope with the help of a very thin needle and fertilization is achieved.

IVF -ICSI program is a process consisting of 4 steps:

Egg Development in the Ovaries

Collecting the Eggs

Fertilization of Eggs and Embryo Development

Placement of the Embryo in the Womb

Who should IVF be applied to?

Tuberculosis and intra-abdominal adhesions

Causes related to men

Ovulation (ovulation) disorder

Unexplained infertility

Other less common causes

Complications that may develop due to in vitro fertilization:

In women:
Overstimulation of the ovaries becomes evident with fluid collection in the abdomen and enlargement of the ovaries.
Bleeding and subsequent infection may develop while the eggs are being collected.
Infection may develop after embryo transfer.

In men:
Bleeding or infection into the testis may be observed in cases where the procedure is performed only by collecting sperm from the testis.

In pregnancy:
The risk of miscarriage is higher than normal.
The risk of premature birth and stillbirth is not higher than normal.
The risk of abnormal baby development is slightly increased, although controversial.
Multiple pregnancy rates are higher than normal.
The development of ectopic pregnancy is higher than normal.

What is the Success Rate in IVF?
Different rates are given in various IVF centers considering different criteria. Some of these can be misleading. There are some factors that affect the success of each center. But to state an average success rate:
The rate at which each attempted IVF procedure results in a live birth:

30-35% in women under 35

25% in women aged 35-37

15-20% in women aged 38-40

6-10% in women over 40

Although the pregnancy rates per cycle are 10-20% higher than these percentages (for example, the pregnancy rates under the age of 35 are 55-60%), it should not be forgotten that the important thing is the percentage of children who can be taken home.

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