In vitro fertilization can be performed for couples who do not have a chance to conceive naturally or who cannot conceive despite trying other treatment methods for a certain period of time, the female eggs are taken out of the body with special needles and combined with male sperm in the laboratory with special techniques and the embryos (babies) obtained are placed in the mother’s womb to create a pregnancy. It’s called the baby app.
The first idea of in vitro fertilization started in the 1960s, after many unsuccessful attempts, in 1979 in England, Dr. Edwards and his team provided the birth of a live child for the first time with the in vitro fertilization method. Louise, the first baby born via IVF It is Brown.
While the in vitro fertilization method was applied to patients with tube blockage in the first years, today detube baby application is performed for sperm problem –endometriosis (chocolate cyst)-unexplained infertility-recurrent miscarriages and selection of a healthy baby.-
Stages of IVF Treatment:
IVF treatment consists of 4 stages.
First stage of IVF treatment development of eggs is In the normal cycle, one egg develops every month, whereas in IVF treatment, more eggs are needed to increase the chance of success. A large number of eggs are developed by using drugs similar to the hormones produced in our body. When the eggs reach a sufficient size (17-19 mm), a cracking needle is made for the eggs to crack and mature. Egg collection is done 34-36 hours after the cracking needle is made.
Second stage in IVF treatment collection of eggs is. Eggs are collected under ultrasound guidance with specially developed needles to collect eggs under general anesthesia or local anesthesia. While it was a difficult procedure performed by laparoscopy in the first years of IVF treatment, now it has become a very easy and low risk procedure. There is no need for hospitalization after egg collection, and it is a daily application. After the procedure, the patient can go home after two or three hours.
Third stage in IVF treatment fusion of egg and spermis
In the classical in vitro fertilization method, eggs and sperms were placed in the same area and one of the sperm was expected to fertilize the egg.
It is not used much today.
The second method is the ICSI method, which is one of the groundbreaking methods in IVF. A sperm is taken and placed directly into the egg. Thus, even with a very small number of sperm, patients have a chance to become pregnant. We have a patient who has a child and only 3 sperms were found as a result of TESE (Sperm search from the testicles by surgery)
Placement of sperm in the egg
In vitro fertilization is the fourth stage. placing babies (embrio) in the wombis
Embryos, which are expected to grow in special temperatures and special environments, are placed in the mother’s womb after 2-5 days. If we have enough embryos (baby) on hand, the transfer process is extended to the 5th day in order to choose the best embryo among them (blastocyst transfer). The transfer process in IVF is a painless and very easy procedure. Although it is very easy, it is the last and most important step of the treatment. In the laboratory, the embryos are placed into the catheter and after that catheter is placed in the mother’s uterus, the embryo is released into the uterus under ultrasound guidance, and then the catheter is withdrawn. It is not necessary to rest for a long time after the transfer, and it is possible to return to daily life the next day.
Embryo transfer process in IVF
In IVF, drugs containing progesterone are used to support the placement of the baby in the uterus after the transfer. With the bhcg test to be performed on the 10th day after the transfer, it is checked whether pregnancy has occurred or not. After 3 weeks, pregnancy is checked with ultrasound.
Kiss. Dr. ÖZGÜR CETINER