Hashimoto’s disease is an autoimmune thyroid disease in which the body’s immune system attacks its own thyroid gland, in which thyroid cells lose their function.

Its incidence is 0.3-1.5 per 1000, and it is seen much more frequently (5-20 times) in women than in men. Thyroid hormone deficiency develops in 4-5% of patients each year. It is most common in women aged 30-50 years.

As a result of Hashimoto’s disease, thyroid hormone deficiency (hypothyroidism) develops.


  • Fatigue and drowsiness and/or weakness

  • Cold intolerance and feeling very cold

  • difficulty concentrating or thinking

  • Depression

  • Getting fat

  • Enlargement or presence of goiter in the neck and shrinkage or shrinkage of the thyroid gland in the later stage of the disease

  • menstrual irregularities, difficulty conceiving

  • Constipation

  • Joint or muscle pain

  • Hair loss

  • dry skin

  • brittle nails

  • Swelling of the face and sometimes the whole body

Women are more likely to get Hashimoto’s disease. The disease can occur at any age, but more often occurs in middle age (30-50 years). Your risk for Hashimoto’s disease is higher if your family members have thyroid or other autoimmune diseases.

If left untreated, thyroid hormone deficiency caused by Hashimoto’s disease can lead to stomach and intestinal problems such as goiter, heart diseases, high cholesterol, blood pressure abnormalities, constipation, and decreased sexual desire in men and women.

Patients with hypothyroidism should be treated with thyroid hormone (levothyroxine). In patients receiving treatment, the dose of levothyroxine should be adjusted by looking at thyroid hormone levels at intervals of 3-6 months. Levothyroxine is best taken in the morning on an empty stomach with water, at least half an hour before eating or drinking anything. Since stomach drugs, calcium, iron, cholesterol-lowering drugs and multivitamins may affect the absorption of the drug, there should be an interval of at least four hours between taking thyroxine and these drugs.

Thyroid hormones should be monitored more frequently during pregnancy and levothyroxine treatment should not be discontinued.

Most patients with Hashimoto’s disease require lifelong treatment with levothyroxine.

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