Fillers are substances that are used to correct the superficial and deep wrinkles of the face, neck, hands and applied to the skin and subcutaneous areas.
The ideal filler should be FDA-approved, non-carcinogenic/teratogenic/allergic, should remain where it is injected, should not displace, should not cause visible permanent skin changes such as redness, infection, foreign body reaction at the injection site, and should be permanent, tissue compatible, and affordable. . For this reason, NASHA, that is, “synthetic Hyaluronic Acid of non-animal origin” has been used successfully as a filler in recent years.
Hyaluronic acid is the main ingredient of the gel-like matrix between cells in normal human soft tissues (skin, cartilage, bone, nerve). It has a water holding capacity of about 1000 times its volume, thus it is responsible for the moisture and elasticity of the skin.
From the age of 30, the amount of hyaluronic acid (HA) of the skin begins to decrease, and this manifests itself in the form of drying on the skin and an increase in fine and thick wrinkles. After menopause, the amount of HA decreases rapidly and the skin becomes thinner and drier, wrinkles increase, facial oval, neck, arms, inner legs, chest sagging parallel to gravity, and collapse in bone structures become evident.
NASHAs, which are widely used today, can be injected into different layers of the skin for different purposes. For example, when applied to the uppermost layer of the epidermis of the skin (with mesotherapy methods, youth vaccine, in the form of light fillers or in a cosmetic mask, moisturizing serum), it moisturizes the skin and increases its brightness, while when applied to the middle skin (dermis), it removes wrinkles (thin and deep). When given subcutaneously, it increases the volume and reshapes it (lip, cheek, chin, nose). It can also be given under sunken scars (for example, acne scars) and reduces the appearance of sunken scars.

Is there a risk of allergy in filler applications?
The risk of allergies associated with NASHAs, which first received FDA approval in 2003, is very low. Less than 0.4% have been reported to date.

How is the filler application done?
The patients are first evaluated by the physician and it is decided what type of filler should be applied for which purpose.
Then the application area is marked and anesthetized with local anesthesia. After anesthesia, the area is disinfected and photographed before the application. After the application is completed, bleeding control is achieved, the physician distributes the product to the tissue by massage. A little cold application is applied to reduce edema. At the end of the procedure, the patient is asked to evaluate himself with a mirror. Then, post-application photography is done. This whole application takes about 20-30 minutes.
Although the fillers may vary according to the age of the patient and the application technique, they remain in the place where they are applied for an average of 6-12 months. However, it is never completely lost. Permanence can be extended up to 18 months in repeated applications.

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