Cryotherapy – Cryopreservation with Cold Gas


It is a form of treatment that has been practiced since the time of the Egyptians and Hippocrates. Ice cream is also known as snow or cold treatment. It shows its effect by causing tissue destruction in order to destroy the diseased tissues in the applied area.

The gas to be used in the freezing process is passed through the probe and causes the tip of the probe to become extremely cold. When the gas used in cooling is pushed to the tip of the probe with pressure, the gas suddenly expands in volume and the tip of the probe cools while absorbing heat from the surroundings. The death of the cell occurs by turning the pure water inside and outside the cell into ice crystals with the effect of cold. For this, solid carbon dioxide at -78.5 °C (dry ice) Cryogenic substances such as -190°C liquid nitrogen, fluorocarbon and nitrous oxide are used. Cold is applied to the tissues with tools called cryocother made of silver or copper.

In which diseases can it be used?

  • Warts (including genital warts),
  • Molluscum contagiosum,
  • sunspots
  • epidermal cysts,
  • keloid,
  • seborrheic keratosis,
  • actinic keratosis,
  • cheilitis,
  • dermatofibroma,
  • alopecia areata (pelad),
  • severe acne,
  • ingrown nails,
  • It is applied in basal cell skin cancer.

What are the advantages of this method?

  • It allows treatment in some skin tumors without the need for surgery (especially in elderly patients).
  • The recurrence of warts after cryotherapy is less than other methods.
  • Good responses are received in the treatment of sunspots.
  • The risk of serious injury or complications is extremely low.
  • It is fast and easy to apply. It can be done in outpatient conditions.
  • It is cheap and safe.
  • Does not require anesthesia.
  • No change in normal life is required after the procedure. It does not affect sports activities and working life.
  • The risk of bleeding after the procedure is extremely low.
  • Cosmetic results are good.
  • It can be used in pregnant women.

Are there any side effects?

The most important side effect after cryotherapy is pain, swelling and fluid collection in the application area. For this reason, pain relievers can be recommended to patients immediately after the application. After the healing is completed in the application area, discoloration or darkening of the skin may occur.

How long does it take to get results?

The time to get results varies according to the location, depth and size of the lesion. For example, 5-6 sessions are required for the treatment of warts under the feet, while the lesion can heal in 2-3 sessions in areas such as hands, face and genital area.

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