Cholesterol drugs reduce risk of colon cancer

According to recent studies, statin group drugs used to lower blood cholesterol levels reduce the incidence of colon cancer. Stating that statin group drugs are among the most commonly used drugs for cholesterol control all over the world, Anadolu Medical Center Medical Oncology Specialist Prof. Dr. Serdar Turhal said, “There are uncertain observations that this group of drugs reduces the formation of different cancers such as liver cancer, breast cancer, stomach cancer, pancreatic cancer, gallbladder tract cancer. However, the suppressive effect of these drugs on cancer development is thought to be through the RAS gene.

Emphasizing that the risk of colon (intestinal) cancer is known to increase in patients with inflammatory bowel disease, Anadolu Medical Center Medical Oncology Specialist Prof. Dr. Serdar Turhal said, “So far, different drugs have been used for the prevention of this cancer in these patients. There are studies on the effect of pain relievers, blood pressure medications, vitamin D and diabetes medications on reducing the formation of colon cancer. (Is this sentence correct, Sir?) YES The most promising of these, Aspirin, could not be put into routine use because it increased the risk of bleeding. Research with others has also not yielded any definitive results,” he said.

Statin group drugs reduce the risk of colon cancer by 60 percent

In a study reported in 2014, a study with 40 different cholesterol drugs was reviewed and it was reported that these drugs in the statin group reduced the risk of colon cancer by 9 percent, but it was stated that more accurately designed studies were needed for definitive proof, Medical Oncology Specialist Prof. Dr. Serdar Turhal, “In the updated publication reported from New York, 52 separate studies were reviewed and the effect on a total of 11,459,306 individuals was observed. Of these, 2,123,293 were taking statin group drugs, and 9,336,013 were not. Among this group, statin users had a 20 percent lower risk of colon cancer compared to non-users. Of 17,528 patients with inflammatory bowel disease, 1,994 were using statins and 15,534 were not using statins. It was observed that statin use reduced the risk of colon cancer in these patients by 60 percent. As a result, a strong observation has been made that statin group drugs reduce the formation of colon cancer, especially in people with inflammatory bowel disease, and its confirmation is expected to be confirmed by comparative studies.

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